Publications
Selected publications (from the last 5 years)
Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism. Malik Hamaidia, Hélène Gazon, Clotilde Hoyos, Gabriela Brunsting Hoffmann, Renaud Louis, Bernard Duysinx and Luc Willems (2019) JCI Insight 4: e128474
ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms. Sheynkman, et al (2020) Nature Communications 11:2326
Ablation of non-coding RNAs affects bovine leukemia virus B lymphocyte proliferation and abrogates oncogenesis. Roghaiyeh Safari, Jean-Rock Jacques, Yves Brostaux and Luc Willems (2020) PLoS Pathogens 16: e1008502
Epigenetic silencing of HTLV-1 expression by the HBZ RNA through interference with the basal transcription machinery. Hélène Gazon, Pradeep Singh Chauhan, Porquet Florent, Gabriela Brunsting Hoffmann, Roberto Accolla and Luc Willems (2020) Blood Advances 4:5574-5579
A safe and effective vaccine against bovine leukemia virus. Guillermo Suárez Archilla,
Gerónimo Gutiérrez, Cecilia Camusson, Luis Calvinho, Alejandro Abdala, Irene Alvarez,
Marcos Petersen, Lautaro Franco, Gabriel Destefano, Gustavo Monti, Jean-Rock Jacques,
Thomas Joris, Luc Willems* and Karina Trono* (2023) Frontiers in Immunology 13:980514
A proteome-scale map of the SARS-CoV-2 human contactome. Kim et al (2023) Nature Biotechnology 41: 140–149.
Assessment of community efforts to advance network-based prediction of protein-protein interactions. Xu-Wen Wang, et al (2023) Nature Communications 14: 1582.
Excess of blood eosinophils prior to therapy correlates with worse prognosis in mesothelioma. Mégane Willems, Arnaud Scherpereel, Eric Wasielewski, Jo Raskin, Hélène Brossel, Alexis Fontaine, Mélanie Grégoire, Louise Halkin, Majeed Jamakhani, Vincent Heinen, Renaud Louis, Bernard Duysinx, Malik Hamaidia, Luc Willems (2023) Frontiers in Immunology 14:1148798.
Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1- associated defects in patient muscle cells. Porquet F., Weidong L., Jehasse K., Gazon H., Kondili M., Blacher S., Massotte L., Noël A., Di Valentin E., Furling D., Gillet N.A., Klein A.F., Seutin V. and Willems L. (2023) Molecular Therapy 32:857-871
The helicase-like transcription factor redirects the autophagic flux and restricts human T-cell leukemia virus type 1 infection. Aurélie Beauvois, Hélène Gazon, Pradeep Singh Chauhan, Majeed Jamakhani, Jean- Rock Jacques, Marc Thiry, Emmanuel Dejardin, Emmanuel Di Valentin, Jean-Claude Twizere, Jean-Marie Péloponèse, Makon-Sébastien Njock, Jun-Ichirou Yasunaga, Masao Matsuoka, Malik Hamaïdia and Luc Willems (2023) Proc. Natl. Acad. Sci. U.S.A. 120: e2216127120
Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis. Thomas Joris, Thomas Jouant, Jean-Rock Jacques, Lorian Gouverneur, Xavier Saintmard, Vilanova Mañá Lea, Majeed Jamakhani, Michal Reichert and Luc Willems (2024) PLoS Pathogens, 20:e1012659
The impact of Charcot-Leyden Crystal protein on mesothelioma chemotherapy: targeting eosinophils for enhanced chemosensitivity. Mégane Willems, Malik Hamaidia, Alexis Fontaine, Mélanie Grégoire, Louise Halkin, Lea Vilanova Mañá, Roxane Terres, Majeed Jamakhani, Sophie Deshayes, Yves Brostaux, Vincent Heinen, Renaud Louis, Bernard Duysinx, Didier Jean, Eric Wasielewski, Arnaud Scherpereel, Christophe Blanquart and Luc Willems (2024) The Lancet eBioMedicine, 109:105418
